Chrom Best Method

Automated Evaluation and Selection of Optimal Chromatographic Methods 

About Chrom Best Method

Chrom Best Method is a vendor-agnostic tool that automatically analyses and compares data from multiple chromatographic methods, then suggests the one most likely to yield a pure compound. Chrom Best Method automates LC-MS data processing, target and impurity identification, method scoring, and report generation, providing quick, smart, and robust answers while still allowing for full review and overriding of results to accommodate users’ needs.

Fast Method
Screening & Selection
Accelerate method selection by automatically scoring and ranking chromatographic methods using your criteria
Fully Automated Workflow
Automate the complete workflow—from data preparation and analysis to reporting—minimizing manual intervention
Clear Visual Insights
Visually inspect method scores, chromatographic profiles, and peak-level data with clarity
Flexible Yet Transparent
Customize scoring logic, review results, and override decisions when needed without losing control

Features

Vendor-Neutral Data Support: Chromatographic data from multiple vendors is supported without requiring format conversion.

Flexible Target Definition: Provide target information via structure files, dataset files, mapping files, or acquisition parameters.

Powerful Target & Impurity Detection: The software enables robust target peak assignment and automatic detection of impurities.

Configurable Scoring Rules: Objectively ranks chromatographic methods with user-defined scoring criteria.

Chiral Screening Optimization: Chrom Best Method evaluates chiral separations using algorithms for enantiomeric resolution comparison.

Multi-Target Method Screening: Evaluates multiple methods and targets simultaneously in a single run.

Batch Reporting: Chrom Best Method generates standardized reports for method review and efficient team sharing.

Review-by-Exception Workflow: Flags critical results for review, allowing experts to adjust analysis and override the results only when necessary.

Benefits

Greater Confidence in Results: Vendor neutrality and consistent scoring improve repeatability and comparability across instruments and projects.

Faster, Clearer Decisions: Automation and visual reports cut through complexity to highlight the optimal method.

Smarter Use of Expertise: Eliminate repetitive manual analysis and focus expertise where it matters most.

Controlled Automation: Chrom Best Method delivers faster, repeatable results while keeping expert review and full scoring control.​

Scalable Performance: Handle numerous methods and targets without slowing down your purification workflow.


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